Paraxanthine is a revolutionary new energy source that is isolated and refined from the caffeine compound. They use Paraxanthine in Update’s formula to enable users to obtain the benefits of caffeine without any side effects.
From their white paper:
Paraxanthine, or 1,7-dimethylxanthine, is a natural dietary component, and the main metabolite of caffeine in humans. The substance, like caffeine can be synthesized for use and also occurs naturally in various plant species like grapefruit, cocoa, and tea. When caffeine is broken down in the liver, ~80% of it converts to paraxanthine.
Like caffeine, paraxanthine is a central nervous stimulant with similar anti-adenosine actions, though research has consistently reported that paraxanthine exhibits slightly higher binding potency for adenosine A1 and A2A receptors. Essentially, this means paraxanthine promotes wakefulness and enhance alertness more effectively than caffeine.
Benefits of Paraxanthine
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The wake-promoting effect of caffeine is the most desirable to consumers, and paraxanthine has proven to be a more effective agent for promoting wakefulness due to its greater affinity for A1/A2 adenosine receptors in the brain.
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Paraxanthine does not induce sleep rebound, hypothermia, or anxiety, while caffeine does.28
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Unlike caffeine, paraxanthine provides neuroprotective benefits by warding against dopaminergic cell death. This suggests that paraxanthine is a better wake-promoting supplement for normal consumption, as well as those suffering from neurological conditions.
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Paraxanthine benefits sustained attention, reaction time, and short-term memory.
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It helps with reasoning and response time to cognitive challenges, as well as help sustain attention.
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There were no additional benefits when caffeine was added to paraxanthine supplementation.
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Human studies with paraxanthine have not reported withdrawal effects previously noted with caffeine.
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Paraxanthine may play a role in increased lipolysis (burning fat).
You can read the full paper here.
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